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Postpartum Hemorrhage (FL INITIAL Autonomous Practice- Pharmacology)

2 Contact Hours including 2 Advanced Pharmacology Hours
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This peer reviewed course is applicable for the following professions:
Advanced Practice Registered Nurse (APRN)
This course will be updated or discontinued on or before Thursday, December 17, 2026

Nationally Accredited

CEUFast, Inc. is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. ANCC Provider number #P0274.


Outcomes

≥ 92% of participants will know how to recognize and respond to a postpartum hemorrhage

Objectives

After completing this continuing education course, the participant will be able to:

  1. Define postpartum hemorrhage.
  2. List the risk factors for postpartum hemorrhage.
  3. Assess for postpartum hemorrhage risk.
  4. Interpret the methods to identify postpartum hemorrhage.
  5. Identify how to care for women with postpartum hemorrhage.
  6. Explain the medications used to treat postpartum hemorrhage.
  7. Determine how to provide care for family members and caregivers following a postpartum hemorrhage.
  8. Describe the necessary follow-up care that women with postpartum hemorrhage require.
CEUFast Inc. and the course planners for this educational activity do not have any relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

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Author:    Kelly LaMonica (DNP(c), MSN, RNC-OB, EFM)

Overview of Postpartum Hemorrhage

Postpartum hemorrhage, or PPH, is a leading cause of maternal morbidity and mortality worldwide. Postpartum hemorrhage is a low volume, high-risk event that labor and delivery (L&D) nurses need to be prepared for. Rapid recognition and response are necessary to prevent the progression of hemorrhage as women can lose large volumes of blood very quickly due to the physiologic changes of pregnancy (California Maternal Quality Care Collaborative [CMQCC], 2022).

Early identification of abnormal blood loss helps to prevent major hemorrhage. The 4 areas that need to be addressed for all women giving birth include (CMQCC, 2022):

  1. Readiness
  2. Recognition
  3. Response
  4. Reporting

Postpartum hemorrhages can occur prior to birth, early postpartum (within the first 24 hours), or late postpartum (≥ 24 hours postpartum), but there is no single definition of hemorrhage (CMQCC, 2022). A commonly used definition of > 500 mL of blood loss for a vaginal birth and > 1,000 mL of blood loss for a cesarean birth is inconsistent and not related to morbidity but may be useful as an alert for concern.

In healthy women, blood loss is generally tolerated without vital sign changes until the total loss exceeds 1,000 mL (CMQCC, 2022)In 2017, the American College of Obstetricians and Gynecologists (ACOG) amended their definition of postpartum hemorrhage from the ‘classic’ description above to cumulative blood loss of ≥ 1000 mL or bleeding associated with signs and symptoms of hypovolemia within 24 hours of birth, regardless of the delivery route (American College of Obstetricians and Gynecologists [ACOG], 2017).

Incidence of Postpartum Hemorrhage

Across the world, postpartum hemorrhage accounts for 8% of maternal deaths in developed countries and up to 20% of maternal deaths in developing countries (Deniau et al., 2024; Bienstock et al., 2021). In the United States, the overall rate of postpartum hemorrhage has been increasing since 2000. In fact, in 2018 alone, there were 17 maternal deaths per 100,000 births in the US (CMQCC, 2022).

Pathophysiology of Postpartum Hemorrhage

Image 1:
Placenta

graphic showing placenta placement in cervex

In late pregnancy, uterine artery blood flow is about 500-700 mL/min. This blood flow is approximately 15% of the woman's cardiac output.

Image 2:
Placenta Circulation

graphic showing placenta circulation

In a normal delivery, once the placenta detaches from the uterus (and delivers), the myometrium contracts, which compresses blood vessels and maintains hemostasis (Bienstock et al., 2021). Coagulation then begins (Bienstock et al., 2021).

There are numerous causes of postpartum hemorrhage. Consider the 4 "Ts" when evaluating a postpartum hemorrhage (McLintock, 2020):

  1. Tone
  2. Trauma
  3. Tissue
  4. Thrombin

Regarding tone, uterine atony, or a lack of uterine tone, is the largest cause of hemorrhage, accounting for 70-80% of all postpartum hemorrhages (Wormer et al., 2023). When looking for lacerations, hematoma, or a ruptured uterus, trauma is what should be considered. The third "T", tissue, refers to retaining placental tissue, and the last "T", thrombin, refers to coagulopathy. The patient may have an undiagnosed bleeding disorder or may have disseminated intravascular coagulation (DIC) (Wormer et al., 2023).

Risk Factors for Postpartum Hemorrhage

Many factors can raise the risk of postpartum hemorrhage, although there can also be postpartum hemorrhage without risk factors.

However, even up to 40% of postpartum hemorrhage occurs in women without any risk factors at all (Cleveland Clinic, 2022).

The risk factors for postpartumhemorrhage include(ACOG, 2017):

Table 1: Risk Factors for Postpartum Hemorrhage
Atony (Tone)
  • Prolonged use of oxytocin
  • High parity
  • Chorioamnionitis
  • Multiple gestation
  • Polyhydramnios
  • Macrosomia
  • Uterine fibroids
  • Fundal implantation of the placenta
  • Uterine inversion
  • Use of Magnesium Sulfate
Trauma
  • Episiotomy
  • Cervical, vaginal, or perineal lacerations
    • Vaginal delivery with forceps or vacuum
    • Precipitous delivery
Tissue
  • Retained placenta
    • Incomplete placenta at delivery
  • Placenta accreta
Thrombin (Coagulation)
  • Preeclampsia
  • Inherited clotting disorder
  • Infection
  • Amniotic fluid embolism
  • Sepsis

(ACOG, 2017)

It is important to recognize that a history of severe postpartum hemorrhage puts the woman at a risk for a subsequent postpartum hemorrhage as well (CMQCC, 2022).

Postpartum Hemorrhage Risk Assessment

Postpartum hemorrhage risk assessments should be performed upon (CMQCC, 2022):

  • Admission
  • Pre-birth (at start of second stage of labor)
  • Post-birth (transfer to postpartum)
  • With any change in the patient’s condition

The Association for Women's Health, Obstetric, and Neonatal Nursing (AWHONN) created one version of a postpartum hemorrhage risk assessment that can be used to assess women for their risk of postpartum hemorrhage, as did the California Maternal Quality Care Collaborative (CMQCC).

This tool is comprehensive because it looks at admission, pre-birth, and post-birth factors, all of which can affect a woman's risk of hemorrhage. The tool even gives suggestions for interventions based on the woman's risk. For example, a woman who is low-risk only needs a "type and hold" order from the blood bank, but a woman who is medium-risk should have a "type and screen" from the blood bank, and certain personnel should be notified of the risk (provider, charge RN, anesthesia, blood bank). A high-risk woman should have a "type and cross," notify personnel and possibly deliver at a tertiary care center (Colalillo et al., 2021).

To view this tool from AWHONN, please visit here. Then, click on the very first link at the top of the page with the title, “AWHONN’s Postpartum Risk Assessment Tool”.

The CMQCC also has a postpartum hemorrhage risk assessment similar to the AWHONN tool. To view the comprehensive tool from the CMQCC, please visit here. You will be asked to download a PDF version of the OB hemorrhage toolkit “Appendix K”, which contains the postpartum hemorrhage risk assessment as discussed above (CMQCC, 2022).

With any risk assessment, it is important to remember that admission risks will remain, but labor and delivery can impose new risks to the woman. Although postpartum hemorrhage can occur without any risks, a woman who is a moderate or high-risk patient should alert the nurse and providers to be prepared for the possibility of a postpartum hemorrhage at delivery (Colalillo et al., 2021).

Special consideration must be given to women who choose not to accept blood products, such as a woman who is a Jehovah's Witness. Women who are Jehovah’s Witnesses should be identified and counseled prenatally. The woman should be given information and a checklist to fill out, stating which products she wishes to receive or not receive. The woman should have a designated healthcare proxy. Some women will accept certain products, such as her blood, from a cell salvage system. It is important to have a care plan for this woman and have the information available at the hospital. It is also important that these women have their hematocrit measured regularly near the end of pregnancy so the woman can take iron, including intravenous iron as needed to optimize their hematocrit (CMQCC, 2022). These patients are at high-risk and have special needs before delivering their babies (CMQCC, 2022).

Identification of Postpartum Hemorrhage

Accurate measurement of blood loss is essential for recognizing potentially life-threatening hemorrhages and the management of blood product replacement (CMQCC, 2022).

Visual Identification

Visual identification of blood loss has been used in the past. However, there are serious problems with the visual estimation of blood loss, as it can be very subjective. Amniotic fluid can also impact the volume that is being identified. Providers tend to underestimate large blood loss volumes, leading to delayed treatment and increased complications for the woman.

Quantitative Blood Loss

Both AWHONN and the CMQCC recommend ‘quantitative blood loss’ for quantifying the amount of blood loss that occurs postpartum. Quantitative blood loss measures the amount of blood loss.

Quantitative blood loss requires the L&D staff to measure all blood lost by using an under the buttocks drape with a graduated collection container that will allow the staff to collect and measure the amount of blood in the drape.

It is important that before the delivery of the baby, the RN or provider must look at the amount of amniotic fluid in the drape. The same thing is done in the canisters of an operating room (OR) for a cesarean section. The amount of amniotic fluid is deducted from the total amount of fluid. The other items soaked with blood (i.e., lap pads, Raytex, Chux Pads) are also weighed (1 gram = 1 mL). The dry weight of each item is needed. The total, less dry weight is then subtracted to calculate blood loss (CMQCC, 2022).

It can be difficult and time-consuming to perform quantitative blood loss, but it is important for an accurate blood loss measurement. There are also newer products, such as Triton, which is a mobile application that calculates hemoglobin content to determine blood loss, which are costly, but may improve accuracy and decrease barriers (Stryker, n.d.).

Response to Postpartum Hemorrhage

As soon as postpartum hemorrhage is recognized, treatment must begin. The evidence shows that it works best for unit-standard, stage-based obstetric hemorrhage emergency management plans with checklists (CMQCC, 2022). There are many components to this. Current evidence recommends that oxytocin be given as a third stage of active management (after delivery). This dosage has decreased the chance of postpartum hemorrhage (CMQCC, 2022).

It is important to know that signs of hypovolemia may not occur until there is larger blood loss (CMQCC, 2022).

Please reference the following table, table 2, to review the associated clinical signs and symptoms that are common depending on a specific volume of blood loss (CMQCC, 2022):

Table 2: Signs of Hypovolemia
Amount of Blood LossClinical Signs
1000 mL
  • Heart rate normal; Palpitations
  • Respiratory rate normal
  • Slight change in blood pressure
  • Dizziness
  • Normal urine output
1500 mL
  • Heart rate over 100 bpm
  • Respiratory rate 20-30 bpm
  • Narrowed pulse pressure*
  • Diaphoretic
  • Weak
  • Urine output decreased to 20-30 mL/hr
2000 mL
  • Heart rate over 120 bpm
  • Respiratory rate 30-40 bpm
  • Hypotension
  • Narrowed pulse pressure
  • Pale
  • Extremities cool
  • Restlessness
  • Urine output decreased to 5-15 mL/hr
≥ 2500 mL
  • Profound hypotension
  • Heart rate over 140 bpm
  • Respiratory rate over 40 bpm
  • Slight urine output or anuria

*Pulse pressure is the difference between the systolic and diastolic blood pressure.
(CMQCC, 2022)

Care of the Patient

It is also important to remember that when the patient starts bleeding heavier than normal, uterine atony is usually the cause.

Image 3:
Uterine Atony

graphic showing uterine atony

However, no matter what the cause, when the nurse determines there is heavy bleeding, it is important to perform a thorough assessment, perform fundal massage, ensure the patient’s bladder is empty, and stay with the patient while help is called. The cause of the hemorrhage will determine specific treatments needed, but there are still general principles that should be applied to all hemorrhages. For uterine atony, the treatment is bimanual uterine massage.

Image 4:
Bimanual Uterine Massage

graphic showing bimanual uterine massage

The nurse can massage the fundus while the provider provides internal uterine massage. Oxytocin is also administered, then uterotonic medications would be used, followed by uterine tamponade with a Bakri balloon or Jada device.

Image 5:
Uterine Balloon Tamponade

graphic showing uterine balloon tamponade

Last options include a B-lynch suture, uterine artery embolization, or finally a hysterectomy (Bienstock et al., 2021).

When considering causes for the postpartum hemorrhage, the provider also needs to assess for tissue, such as a retained placenta. If there is retained placenta, the provider may be able to remove it manually or the patient may need removal by curettage (Bienstock et al., 2021). The provider should also assess for trauma, looking for any lacerations that need to be repaired by suture (Bienstock et al., 2021). Thrombin reasons for PPH will be addressed by treating with blood products.

Stages of Postpartum Hemorrhage

There are numerous checklists and algorithms that exist that outline the stages of hemorrhage. These checklists are similar, and each hospital should choose one to use to guide their efforts. The ideal algorithm has all the stages on one page, for clarity and best ease of use (CMQCC, 2022). Some algorithms have a page for each stage of hemorrhage and treatment.

Stage 1

There may be some differences in definitions within each algorithm, depending on the one your unit or organization might choose to utilize.

Generally, stage 1 occurs when there is blood loss of > 500 mL in vaginal birth and > 1000 mL in a cesarean section, but under 1500 mL of blood loss.

During stage 1, the RN should establish intravenous (IV) access if not present, increase IV oxytocin rate, apply vigorous fundal massage, and start administering medication. The RN should also obtain the patient’s vital signs, including O2 saturation and level of consciousness (LOC). This should occur within 5 minutes. The RN should administer oxygen to maintain O2 sats at > 95% as needed. The patient should have her bladder emptied with a straight catheter or foley and a type and crossmatch obtained for 2 units of red blood cells STAT. Providers and RN should be discussing the root cause of her postpartum hemorrhage so that mitigation can begin.

Stage 2

Stage 2 occurs when the bleeding continues but is < 1500 mL.

The patient should have additional medications, a second IV, and blood should be brought to the bedside. Labs should be ordered. The reason for postpartum hemorrhage still needs to be determined. The patient may need to go to the OR. A uterine tamponade balloon may be useful at this point. These can treat postpartum hemorrhage with the action of physically compressing blood vessels within the uterus. All obstetric providers should be trained to use a uterine tamponade balloon. The RN may assist by filling the balloon as directed by the manufacturer. There is a newer intrauterine vacuum device, known as the Jada device, that can also be inserted into the uterus and connected to low section. It causes contractions and constriction of blood vessels (CMQCC, 2022).

Stage 3

Stage 3 occurs when blood loss is >1500 mL, the patient has had at least two units of blood, or if they are unstable.

At this time, all emergency personnel, including anesthesia, should be present. The massive transfusion protocol should be activated. The patient will need blood and blood products. A body and fluid warmer should be used at this time. The patient may need central hemodynamic monitoring. The patient may also need a hysterectomy or uterine artery ligation. This woman is at risk of shock and cardiac arrest (CMQCC, 2022). She may require close observation in the intensive care unit (ICU) once the crisis has passed.

All labor and delivery units should be prepared for hemorrhage. Every unit should have all medications available immediately. Each unit should also have a cart with hemorrhage supplies and checklists ready. A uterine tamponade balloon with instructions should also be included in the cart. Hospitals should also have a response team for this type of emergency, a massive transfusion protocol, and emergency blood release checklists (CMQCC, 2022). Labor and delivery units should also be conducting hemorrhage drills with L&D staff and providers. Drills allow the staff to improve communication and readiness and determine any barriers to appropriate treatment (ACOG, 2014).

Blood Products

Maternal outcomes improve with early and aggressive blood replacement intervention. Emergency blood release (uncrossed O negative blood) and massive transfusion protocols should be in place.

During a critical obstetric hemorrhage, transfusion should be based on the patient’s vital signs and blood loss amount and should not be delayed by waiting for laboratory results. It is often necessary to administer calcium replacement with massive transfusion due to the citrate used for anticoagulation in blood products. During the transfusion, the patient's electrolytes, arterial blood gas (ABG), and core temperature should be monitored, and all transfused fluids should be warmed prior to infusion. The patient should also be warmed to maintain euthermia and avoid added risk of coagulopathy (CMQCC, 2022).

Medications for Postpartum Hemorrhage Treatment

There are numerous medications used to treat postpartum hemorrhage. The following uterotonic agents are used to help the uterus contract (CMQCC, 2022):

  • Oxytocin
  • Methergine
  • Hemabate
  • Cytotec
  • Tranexamic acid (TXA)

Oxytocin

Oxytocin (PitosinTM) should be given after every delivery, and additional oxytocin may be given for hemorrhage (CMQCC, 2022). It may be given intravenous (IV) or intramuscular (IM).

The usual dose is 10 to 40 units (CMQCC, 2022). The infusion rate is typically titrated according to uterine tone (CMQCC, 2022).

There are few side effects of oxytocin. However, oxytocin can cause nausea, vomiting, hyponatremia, or increased blood pressure and/or heart rate, generally if pushed via IV and with higher doses (CMQCC, 2022).

Methylergonovine

Methylergonovine (Methergine ®) 0.2 mg IM may be given every 2 to 4 hours (CMQCC, 2022). It cannot be given via IV infusion. If there is no response to the initial dose, it is generally considered unlikely that additional doses will be of benefit (CMQCC, 2022).

This medication must be refrigerated and protected from light (CMQCC, 2022).

Nausea, vomiting, and hypertension are possible side effects of Methergine ®, most notably due to rapid administration or with patients who have hypertension (CMQCC, 2022). A woman with preeclampsia or heart disease should not receive Methergine ®.

Carboprost

Carboprost (Hemabate ®) 250 mcg IM may be given every 15 to 90 minutes (CMQCC, 2022). Although Hemabate ® cannot be administered via IV, in addition to intramuscularly, it can be given via the intra-myometrial route (CMQCC, 2022). If there is still no response after three doses of Hemabate ®, it is said that it is unlikely that any additional doses will have any benefit at all (CMQCC, 2022).

This medication must be refrigerated (CMQCC, 2022).

Hemabate ® can cause nausea, vomiting, diarrhea, shivering, a transient fever and chills, and possible bronchospasm (CMQCC, 2022). This medication should not be given to women with asthma, hepatic disease, cardiac disease, or pulmonary disease (CMQCC, 2022).

Misoprostol

Misoprostol (Cytotec ®) is available as 100 or 200 mcg tablets (CMQCC, 2022). The typical dose is 600-800 mcg, and it may be given sublingual (SL) or orally (CMQCC, 2022).

Cytotec ® is administered a single time (CMQCC, 2022).

Nausea, vomiting, headache, diarrhea, and transient fever with shivering are all side effects of Cytotec ® (CMQCC, 2022). The only rare case of contraindications to taking Cytotec ® is in the case of a known allergy to prostaglandin (CMQCC, 2022).

Tranexamic Acid (TXA)

Tranexamic acid (TXA) is a lysine analog and antifibrinolytic agent that is also being used in some L&D units to stop bleeding. This medication is given IV piggyback over ten minutes and must be reconstituted before use. The standard dose is 1 gm (CMQCC, 2022).

The first dose should be administered within three hours of identifying a postpartum hemorrhage (CMQCC, 2022). A second dose is recommended if bleeding continues after another 30 minutes or if bleeding stops and then begins again within 24 hours of the completion of the first dose (CMQCC, 2022).

Tranexamic acid (TXA) can cause nausea, diarrhea, vomiting, or potentially hypotension if it is administered too quickly (CMQCC, 2022). Possible contraindications can include a known thromboembolic event during pregnancy, an active intravascular clotting issue, or a coagulopathy history (CMQCC, 2022).

Debriefing

Debriefing after an emergency, such as a postpartum hemorrhage, is also vital to the caregivers. Every stage 2 or 3 hemorrhages should have a debriefing. Conducting a debrief creates a safety culture in L&D.

Debriefing should also be confidential. It is not something that is part of the patient record. Debriefing is used to determine what went well and identify barriers to giving the best care. Debriefing improves communication among all involved and makes the unit safer (Tirelli & Colpa-Lewis, 2017). Debriefing also helps caregivers process their feelings about the emergency.

Impact on Patient, Family, & Caregivers

Postpartum hemorrhage is a traumatic experience for the woman, her family, and the caregivers. During a crisis, it is difficult to explain what is happening. Studies have shown that some women never receive an explanation of what happened. The woman needs to know what happened and why it happened so she can process the event.

During the crisis, it may also be beneficial to the woman and the family if the family can stay with the patient. It is important to provide a calm, healing environment after the crisis. Attention to the woman's emotional status is important. If needed, she must be assessed for acute trauma and referred to counseling services (CMQCC, 2022). Caregivers may also experience acute trauma and should seek resources as needed. Most hospitals have an employee assistance program (EAP) that can help to start the process.

Care After Postpartum Hemorrhage

A patient who has had a postpartum hemorrhage should be educated about signs and symptoms to look out for (CMQCC, 2022).

These signs and symptoms that should not be ignored include (CMQCC, 2022):

  • Heavy bleeding (soaking a pad an hour)
  • Large blood clots
  • Feeling dizzy when standing
  • Abdominal pain
  • Headache
  • Blurry vision
  • Feelings of depression
  • Feelings of numbness
  • Feelings of anxiousness

Case Study: Casey

Casey is a 33-year-old G2P1.

Casey underwent a cesarean section at 9:00pm for a prolonged second stage and arrest of descent after 24 hours of dysfunctional labor, augmentation, and a 4-hour second stage.

Casey’s child, Selena, was born with a birth weight of 4950 grams.

Casey’s pre-operative hematocrit level had been 37%. During surgery, Casey’s blood loss was reported to be 1050 mL, and an extension of the transverse uterine incision was sutured while extending in the left broad ligament.

Casey is now in a postpartum room at midnight and complaining of abdominal pain.

Casey’s 10:00 pm vitals include:

  • Blood pressure: 119/62 mmHg
  • Pulse: 122 bpm

Casey has passed a moderate amount of blood clots. The RN started 5% Dextrose in Lactated Ringer’s (D5LR) with 20 units of Oxytocin running intravenously at 125 mL per hour.

At 11:30 pm, the patient passed even more clots.

Casey’s 11:30 pm vitals include:

  • Blood pressure: 79/39 mmHg
  • Pulse 155 bpm
  • Urine output of less than 20 mL since surgery

Upon the RN’s physical assessment, Casey’s abdomen seems distended.

Let’s take a moment to reflect on this clinical scenario and ask ourselves some questions:

  • Who should manage Casey?
  • Does Casey require an exam or even surgery at this point?
  • What is the most likely cause of Casey’s current symptoms, vitals, and physical signs?
  • What supplies should be readily available to the RN and the rest of the L&D team?
  • Who needs to be mobilized at this point?

Fifteen minutes later, Casey is clearly in shock and oozing from her IV sites and bleeding from her vagina. Casey is then immediately taken to surgery. During surgery, Casey’s incision is opened, revealing a large hematoma in the broad ligament extending retroperitoneally. Bleeding occurs from the left corner uterine incision. Massive transfusion protocol is initiated.

Conclusion

Postpartum hemorrhage is a serious complication of childbirth that increases maternal morbidity and mortality. Postpartum hemorrhage can have long-lasting effects on the woman, her family, and her caregivers. All L&D units must always be prepared for a hemorrhage. Supplies, medications, drills, and debriefings are all necessary tools to improve a woman's care during and after a postpartum hemorrhage.

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Implicit Bias Statement

CEUFast, Inc. is committed to furthering diversity, equity, and inclusion (DEI). While reflecting on this course content, CEUFast, Inc. would like you to consider your individual perspective and question your own biases. Remember, implicit bias is a form of bias that impacts our practice as healthcare professionals. Implicit bias occurs when we have automatic prejudices, judgments, and/or a general attitude towards a person or a group of people based on associated stereotypes we have formed over time. These automatic thoughts occur without our conscious knowledge and without our intentional desire to discriminate. The concern with implicit bias is that this can impact our actions and decisions with our workplace leadership, colleagues, and even our patients. While it is our universal goal to treat everyone equally, our implicit biases can influence our interactions, assessments, communication, prioritization, and decision-making concerning patients, which can ultimately adversely impact health outcomes. It is important to keep this in mind in order to intentionally work to self-identify our own risk areas where our implicit biases might influence our behaviors. Together, we can cease perpetuating stereotypes and remind each other to remain mindful to help avoid reacting according to biases that are contrary to our conscious beliefs and values.

References

  • American College of Obstetricians and Gynecologists. (ACOG). (2017). Committee on Practice Bulletins-Obstetrics: Practice bulletin no. 183: Postpartum hemorrhage. Obstetrics and Gynecology, 130(4), e168–e186. Visit Source.
  • American College of Obstetricians and Gynecologists. (ACOG). (2014). Committee opinion no. 590: Preparing for clinical emergencies in obstetrics and gynecology. Obstetrics and Gynecology, 123(3), 722–725. Visit Source.
  • Belfort, M. (2024). Overview of postpartum hemorrhage. UpToDate. Retrieved February 10, 2024. Visit Source.
  • Bienstock, J. L., Eke, A. C., & Hueppchen, N. A. (2021). Postpartum hemorrhage. The New England Journal of Medicine, 384(17), 1635–1645. Visit Source.
  • California Maternal Quality Care Collaborative (CMQCC). (2022). OB Hemorrhage Toolkit V3.0 Errata. California Maternal Quality Care Collaborative. Visit Source.
  • Cleveland Clinic. (2022). Postpartum hemorrhage. Cleveland Clinic. Visit Source.
  • Colalillo, E. L., Sparks, A. D., Phillips, J. M., Onyilofor, C. L., & Ahmadzia, H. K. (2021). Obstetric hemorrhage risk assessment tool predicts composite maternal morbidity. Scientific Reports, 11(1), 14709. Visit Source.
  • Deniau, B., Ricbourg, A., Weiss, E., Paugam-Burtz, C., Bonnet, M., Goffinet, F., Mignon, A., Morel, O., Le Guen, M., Binczak, M., Carbonnel, M., Michelet, D., Dahmani, S., Pili-Floury, S., Ducloy Bouthors, A. S., Mebazaa, A., & Gayat, E. (2024). Association of severe postpartum hemorrhage and development of psychological disorders: Results from the prospective and multicentre HELP MOM study. Anaesthesia Critical Care & Pain Medicine, 43(2), 101340. Visit Source.
  • McLintock, C. (2020). Prevention and treatment of postpartum hemorrhage: Focus on hematological aspects of management. Hematology: American Society of Hematology Education Program, 2020(1), 542–546. Visit Source.
  • Stryker. (n.d.). Enabling technology to improve maternal care. Stryker. Visit Source.
  • Tirelli, M.A. & Colpa-Lewis, C. (2017). Nurse-led debriefing to create a culture of safety following obstetric emergencies. Journal of Obstetric, Gynecologic & Neonatal Nursing, 46(3). Visit Source.
  • Wormer, K. C., Jamil, R. T., & Bryant, S. B. (2023). Postpartum hemorrhage. In StatPearls. StatPearls Publishing. Retrieved February 10, 2024. Visit Source.