≥ 92% of participants will know how to recognize and respond to a postpartum hemorrhage
CEUFast, Inc. is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. ANCC Provider number #P0274.
≥ 92% of participants will know how to recognize and respond to a postpartum hemorrhage
After completing this continuing education course, the participant will be able to:
Postpartum hemorrhage, or PPH, is a leading cause of maternal morbidity and mortality worldwide. Postpartum hemorrhage is a low volume, high-risk event that labor and delivery (L&D) nurses need to be prepared for.
Early identification of abnormal blood loss helps to prevent major hemorrhage. The 4 areas that need to be addressed for all women giving birth include (CMQCC, 2022):
Postpartum hemorrhages can occur prior to birth, early postpartum (within the first 24 hours), or late postpartum (≥ 24 hours postpartum), but there is no single definition of hemorrhage (CMQCC, 2022). A commonly used definition of > 500 mL of blood loss for a vaginal birth and > 1,000 mL of blood loss for a cesarean birth is inconsistent and not related to morbidity but may be useful as an alert for concern.
In healthy women, blood loss is generally tolerated without vital sign changes until the total loss exceeds 1,000 mL (CMQCC, 2022).
Across the world, postpartum hemorrhage accounts for 8% of maternal deaths in developed countries and up to 20% of maternal deaths in developing countries (Deniau et al., 2024; Bienstock et al., 2021). In the United States, the overall rate of postpartum hemorrhage has been increasing since 2000. In fact, in 2018 alone, there were 17 maternal deaths per 100,000 births in the US (CMQCC, 2022).
Image 1:
Placenta
Image 2:
Placenta Circulation
In a normal delivery, once the placenta detaches from the uterus (and delivers), the myometrium contracts, which compresses blood vessels and maintains hemostasis (Bienstock et al., 2021). Coagulation then begins (Bienstock et al., 2021).
There are numerous causes of postpartum hemorrhage.
Many factors can raise the risk of postpartum hemorrhage, although there can also be postpartum hemorrhage without risk factors.
However, even up to 40% of postpartum hemorrhage occurs in women without any risk factors at all (Cleveland Clinic, 2022).
Atony (Tone) |
|
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Trauma |
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Tissue |
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Thrombin (Coagulation) |
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(ACOG, 2017)
It is important to recognize that a history of severe postpartum hemorrhage puts the woman at a risk for a subsequent postpartum hemorrhage as well (CMQCC, 2022).
The Association for Women's Health, Obstetric, and Neonatal Nursing (AWHONN) created one version of a postpartum hemorrhage risk assessment that can be used to assess women for their risk of postpartum hemorrhage, as did the California Maternal Quality Care Collaborative (CMQCC).
This tool is comprehensive because it looks at admission, pre-birth, and post-birth factors, all of which can affect a woman's risk of hemorrhage. The tool even gives suggestions for interventions based on the woman's risk. For example, a woman who is low-risk only needs a "type and hold" order from the blood bank, but a woman who is medium-risk should have a "type and screen" from the blood bank, and certain personnel should be notified of the risk (provider, charge RN, anesthesia, blood bank). A high-risk woman should have a "type and cross," notify personnel and possibly deliver at a tertiary care center (Colalillo et al., 2021).
To view this tool from AWHONN, please visit here. Then, click on the very first link at the top of the page with the title, “AWHONN’s Postpartum Risk Assessment Tool”.
The CMQCC also has a postpartum hemorrhage risk assessment similar to the AWHONN tool. To view the comprehensive tool from the CMQCC, please visit here. You will be asked to download a PDF version of the OB hemorrhage toolkit “Appendix K”, which contains the postpartum hemorrhage risk assessment as discussed above (CMQCC, 2022).
With any risk assessment, it is important to remember that admission risks will remain, but labor and delivery can impose new risks to the woman. Although postpartum hemorrhage can occur without any risks, a woman who is a moderate or high-risk patient should alert the nurse and providers to be prepared for the possibility of a postpartum hemorrhage at delivery (Colalillo et al., 2021).
Special consideration must be given to women who choose not to accept blood products, such as a woman who is a Jehovah's Witness.
Accurate measurement of blood loss is essential for recognizing potentially life-threatening hemorrhages and the management of blood product replacement (CMQCC, 2022).
Visual identification of blood loss has been used in the past.
Quantitative blood loss requires the L&D staff to measure all blood lost by using an under the buttocks drape with a graduated collection container that will allow the staff to collect and measure the amount of blood in the drape.
It is important that before the delivery of the baby, the RN or provider must look at the amount of amniotic fluid in the drape. The same thing is done in the canisters of an operating room (OR) for a cesarean section. The amount of amniotic fluid is deducted from the total amount of fluid.
It can be difficult and time-consuming to perform quantitative blood loss, but it is important for an accurate blood loss measurement. There are also newer products, such as Triton, which is a mobile application that calculates hemoglobin content to determine blood loss, which are costly, but may improve accuracy and decrease barriers (Stryker, n.d.).
As soon as postpartum hemorrhage is recognized, treatment must begin.
It is important to know that signs of hypovolemia may not occur until there is larger blood loss (CMQCC, 2022).
Amount of Blood Loss | Clinical Signs |
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1000 mL |
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1500 mL |
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2000 mL |
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≥ 2500 mL |
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*Pulse pressure is the difference between the systolic and diastolic blood pressure.
(CMQCC, 2022)
It is also important to remember that when the patient starts bleeding heavier than normal, uterine atony is usually the cause.
Image 3:
Uterine Atony
However, no matter what the cause, when the nurse determines there is heavy bleeding, it is important to perform a thorough assessment, perform fundal massage, ensure the patient’s bladder is empty, and stay with the patient while help is called. The cause of the hemorrhage will determine specific treatments needed, but there are still general principles that should be applied to all hemorrhages. For uterine atony, the treatment is bimanual uterine massage.
Image 4:
Bimanual Uterine Massage
The nurse can massage the fundus while the provider provides internal uterine massage. Oxytocin is also administered, then uterotonic medications would be used, followed by uterine tamponade with a Bakri balloon or Jada device.
Image 5:
Uterine Balloon Tamponade
Last options include a B-lynch suture, uterine artery embolization, or finally a hysterectomy (Bienstock et al., 2021).
When considering causes for the postpartum hemorrhage, the provider also needs to assess for tissue, such as a retained placenta. If there is retained placenta, the provider may be able to remove it manually or the patient may need removal by curettage (Bienstock et al., 2021). The provider should also assess for trauma, looking for any lacerations that need to be repaired by suture (Bienstock et al., 2021). Thrombin reasons for PPH will be addressed by treating with blood products.
There are numerous checklists and algorithms that exist that outline the stages of hemorrhage. These checklists are similar, and each hospital should choose one to use to guide their efforts. The ideal algorithm has all the stages on one page, for clarity and best ease of use (CMQCC, 2022). Some algorithms have a page for each stage of hemorrhage and treatment.
There may be some differences in definitions within each algorithm, depending on the one your unit or organization might choose to utilize.
Generally, stage 1 occurs when there is blood loss of > 500 mL in vaginal birth and > 1000 mL in a cesarean section, but under 1500 mL of blood loss.
Stage 3 occurs when blood loss is >1500 mL, the patient has had at least two units of blood, or if they are unstable.
Maternal outcomes improve with early and aggressive blood replacement intervention.
There are numerous medications used to treat postpartum hemorrhage. The following uterotonic agents are used to help the uterus contract (CMQCC, 2022):
The usual dose is 10 to 40 units (CMQCC, 2022). The infusion rate is typically titrated according to uterine tone (CMQCC, 2022).
There are few side effects of oxytocin. However, oxytocin can cause nausea, vomiting, hyponatremia, or increased blood pressure and/or heart rate, generally if pushed via IV and with higher doses (CMQCC, 2022).
Methylergonovine (Methergine ®) 0.2 mg IM may be given every 2 to 4 hours (CMQCC, 2022). It cannot be given via IV infusion. If there is no response to the initial dose, it is generally considered unlikely that additional doses will be of benefit (CMQCC, 2022).
This medication must be refrigerated and protected from light (CMQCC, 2022).
Nausea, vomiting, and hypertension are possible side effects of Methergine ®, most notably due to rapid administration or with patients who have hypertension (CMQCC, 2022).
Carboprost (Hemabate ®) 250 mcg IM may be given every 15 to 90 minutes (CMQCC, 2022). Although Hemabate ® cannot be administered via IV, in addition to intramuscularly, it can be given via the intra-myometrial route (CMQCC, 2022). If there is still no response after three doses of Hemabate ®, it is said that it is unlikely that any additional doses will have any benefit at all (CMQCC, 2022).
This medication must be refrigerated (CMQCC, 2022).
Hemabate ® can cause nausea, vomiting, diarrhea, shivering, a transient fever and chills, and possible bronchospasm (CMQCC, 2022).
Misoprostol (Cytotec ®) is available as 100 or 200 mcg tablets (CMQCC, 2022). The typical dose is 600-800 mcg, and it may be given sublingual (SL) or orally (CMQCC, 2022).
Cytotec ® is administered a single time (CMQCC, 2022).
Nausea, vomiting, headache, diarrhea, and transient fever with shivering are all side effects of Cytotec ® (CMQCC, 2022). The only rare case of contraindications to taking Cytotec ® is in the case of a known allergy to prostaglandin (CMQCC, 2022).
Tranexamic acid (TXA) is a lysine analog and antifibrinolytic agent that is also being used in some L&D units to stop bleeding. This medication is given IV piggyback over ten minutes and must be reconstituted before use. The standard dose is 1 gm (CMQCC, 2022).
The first dose should be administered within three hours of identifying a postpartum hemorrhage (CMQCC, 2022). A second dose is recommended if bleeding continues after another 30 minutes or if bleeding stops and then begins again within 24 hours of the completion of the first dose (CMQCC, 2022).
Tranexamic acid (TXA) can cause nausea, diarrhea, vomiting, or potentially hypotension if it is administered too quickly (CMQCC, 2022). Possible contraindications can include a known thromboembolic event during pregnancy, an active intravascular clotting issue, or a coagulopathy history (CMQCC, 2022).
Debriefing after an emergency, such as a postpartum hemorrhage, is also vital to the caregivers. Every stage 2 or 3 hemorrhages should have a debriefing. Conducting a debrief creates a safety culture in L&D.
Debriefing should also be confidential. It is not something that is part of the patient record.
During the crisis, it may also be beneficial to the woman and the family if the family can stay with the patient. It is important to provide a calm, healing environment after the crisis.
A patient who has had a postpartum hemorrhage should be educated about signs and symptoms to look out for (CMQCC, 2022).
Casey is a 33-year-old G2P1.
Casey underwent a cesarean section at 9:00pm for a prolonged second stage and arrest of descent after 24 hours of dysfunctional labor, augmentation, and a 4-hour second stage.
Casey’s child, Selena, was born with a birth weight of 4950 grams.
Casey’s pre-operative hematocrit level had been 37%. During surgery, Casey’s blood loss was reported to be 1050 mL, and an extension of the transverse uterine incision was sutured while extending in the left broad ligament.
Casey is now in a postpartum room at midnight and complaining of abdominal pain.
Casey’s 10:00 pm vitals include:
Casey has passed a moderate amount of blood clots. The RN started 5% Dextrose in Lactated Ringer’s (D5LR) with 20 units of Oxytocin running intravenously at 125 mL per hour.
At 11:30 pm, the patient passed even more clots.
Casey’s 11:30 pm vitals include:
Upon the RN’s physical assessment, Casey’s abdomen seems distended.
Let’s take a moment to reflect on this clinical scenario and ask ourselves some questions:
Fifteen minutes later, Casey is clearly in shock and oozing from her IV sites and bleeding from her vagina. Casey is then immediately taken to surgery. During surgery, Casey’s incision is opened, revealing a large hematoma in the broad ligament extending retroperitoneally. Bleeding occurs from the left corner uterine incision. Massive transfusion protocol is initiated.
Postpartum hemorrhage is a serious complication of childbirth that increases maternal morbidity and mortality. Postpartum hemorrhage can have long-lasting effects on the woman, her family, and her caregivers. All L&D units must always be prepared for a hemorrhage. Supplies, medications, drills, and debriefings are all necessary tools to improve a woman's care during and after a postpartum hemorrhage.
CEUFast, Inc. is committed to furthering diversity, equity, and inclusion (DEI). While reflecting on this course content, CEUFast, Inc. would like you to consider your individual perspective and question your own biases. Remember, implicit bias is a form of bias that impacts our practice as healthcare professionals. Implicit bias occurs when we have automatic prejudices, judgments, and/or a general attitude towards a person or a group of people based on associated stereotypes we have formed over time. These automatic thoughts occur without our conscious knowledge and without our intentional desire to discriminate. The concern with implicit bias is that this can impact our actions and decisions with our workplace leadership, colleagues, and even our patients. While it is our universal goal to treat everyone equally, our implicit biases can influence our interactions, assessments, communication, prioritization, and decision-making concerning patients, which can ultimately adversely impact health outcomes. It is important to keep this in mind in order to intentionally work to self-identify our own risk areas where our implicit biases might influence our behaviors. Together, we can cease perpetuating stereotypes and remind each other to remain mindful to help avoid reacting according to biases that are contrary to our conscious beliefs and values.