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Long-Term Care Nursing: Medication Pass

1.5 Contact Hours including 1.5 Pharmacology Hours
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This peer reviewed course is applicable for the following professions:
Advanced Practice Registered Nurse (APRN), Certified Nurse Midwife, Certified Nurse Practitioner, Certified Registered Nurse Anesthetist (CRNA), Certified Registered Nurse Practitioner, Clinical Nurse Specialist (CNS), Licensed Practical Nurse (LPN), Licensed Vocational Nurses (LVN), Midwife (MW), Nursing Student, Registered Nurse (RN), Registered Nurse Practitioner
This course will be updated or discontinued on or before Thursday, October 7, 2027

Nationally Accredited

CEUFast, Inc. is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. ANCC Provider number #P0274.


Outcomes

≥ 92% of participants will know how to identify proper techniques for medication preparation and administration in long-term care, as well as identify causes of medication errors and how to prevent them.

Objectives

After completing this course, the participants will be able to:

  1. Explain the five rights of medication administration.
  2. Compare the common routes of medication administration utilized in long-term care.
  3. List the four types of drug interactions.
  4. Examine abbreviations that are not acceptable according to the “Do Not Use Abbreviation” chart.
  5. Identify high alert medications in long-term care.
  6. Elaborate on the five criteria for the Beers List.
  7. List five or more main causes of medication errors.
  8. Examine three ways to prevent the spread of infection during medication handling.
  9. Outline what the Tall Man Lettering technique is and how it is utilized.
  10. Determine how and when to document medication administration.
  11. Formulate three strategies to prevent activity-based medication errors in long-term care facilities.
CEUFast Inc. and the course planning team for this educational activity do not have any relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

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Long-Term Care Nursing: Medication Pass
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To earn a certificate of completion you have one of two options:
  1. Take test and pass with a score of at least 80%
  2. Reflect on practice impact by completing a course evaluation.
    (NOTE: Some approval agencies and organizations require you to take a test and the course evaluation is NOT an option.)
Author:    Rachel Pugmire (RN, BSN)

Introduction

Long-term care nursing is a very important and needed aspect of healthcare. Long-term care is very rewarding as nurses care for individuals who require assistance with daily life. This type of nursing also presents unique challenges as nurses are required to balance the care of many patients, often with complex comorbidities, who rely on multiple medications to remain healthy. Individuals in long-term care may be geriatric residents, those who are recovering or adapting after a major health event such as a stroke or accident, young individuals with diagnoses that make it difficult or unsafe for them to live independently, or those with memory impairment. Nurses in long-term care must be able to perform a wide variety of skills, utilize their nursing education to perform thorough assessments, be well educated regarding numerous medications, have critical thinking skills, work within their scope of practice, and be exceptional at multitasking as they balance patient loads and provide excellent care.

Medication administration and patient safety are two of nurses' major responsibilities when caring for patients. Proper medication administration and preventing medication errors are crucial to providing safe care for patients in any healthcare setting, especially in long-term care. Proper training, education, and application allow nurses to maintain and uphold safe medication administration techniques to protect patients, themselves, and other health care workers. This course aims to solidify the important aspects of safe medication preparation and administration, bring awareness to common medication errors, and empower nurses with confidence when administering medications.

The Five Rights of Medication Administration

Nurses dispense a wide variety of medications while caring for patients; thus, there is the risk of medication errors. Medication errors can put the patient at risk for serious complications, reactions, or even death. The five rights of medication administration were created to best prevent medication errors when administering medications. The five rights of medication administration are as follows (Hanson & Haddad, 2023):

  1. Right Patient
  2. Right Medication
  3. Right Dose
  4. Right Route
  5. Right Time

As nurses utilize these five rights of medication administration, the incidence of medication errors can significantly decrease, and patient safety can be improved. Review these rights before preparing the medication, after you have prepared it, and again before administering it to the resident.

Five Rights of Medication Administration

graphic showing five rights of medication administration

Right Patient

Ensuring that the correct medication is given to the correct patient and for the right reason is the first step in safe medication administration. This is done by comparing the individual and the prescribed medication to the resident’s medication administration record (MAR).  This ensures that the nurse has correctly verified the individual. Nurses are often required to carry heavy patient loads, so patient verification is key. This is best done by asking the patient their first and last name and their date of birth. Utilizing two patient identifiers is a double check that the right individual is receiving the medication. A room number is not considered a means of identification because residents can move rooms; it is not tied directly to the individual. Many facilities utilize a wristband with a barcode assigned to each individual. Computer-assisted medication administration can significantly help reduce medication errors and notify nurses of discrepancies. It is also important to recognize that residents can have the same first or last name, so proper verification is mandatory.

Residents with certain medical conditions may be unable to speak or understand what is being asked of them. This can pertain to residents with dementia, Alzheimer’s Disease, cognitive impairments, or mental health diagnoses. In some memory care facilities, patients may be unable to verbally identify themselves or remember their name or birthdate. Following facility guidelines in such instances is important to properly identify residents before medication administration.

Right Medication

Medication errors can occur when the incorrect medication is given to a patient. The medication being given must match the medication prescribed. Many factors can lead to the administration of an incorrect medication.

  • Similar names: Some medications have names that sound or look alike and can easily be confused. Other medications may have a similar physical appearance to those with a different indication.
  • Similar packaging: Packaging that looks similar amongst medications can result in misidentification.
  • Poor handwriting: Illegible writing or writing in abbreviations can cause a medication to be administered incorrectly. It is recommended that prescribers write out the full medication name when writing orders and use the generic name to decrease the risk of confusion with other medications that may have similar names. A nurse taking a verbal order should also avoid abbreviations.

To prevent such errors, medications must be thoroughly checked before they are pulled from the pharmacy or dispensing cart, after they have been prepared, and again before they are given to the resident at the bedside.

Nurses must also remember that careful attention to detail is required when multiple medications are due simultaneously for the same resident. Always double-check the medication being given before drawing up, crushing, or pushing it. Check that the correct medication is being handled in each step of medication preparation and administration. If there is any hesitation or question regarding which medication is prescribed, provided, or ordered, the best practice is to verify with the prescribing healthcare professional and/or pharmacist.

Right Dose

Verifying that the correct dose is being administered is extremely important for patient safety; administering too much or too little of a medication can be detrimental. There are many factors to consider when confirming that the correct dose is given to a resident. The dose of the medication itself is important. Additionally, it is important to realize that medication errors can occur when an incorrect concentration of a drug is mixed or prepared. Some medications and situations require conversions, increasing the opportunities for error. Utilize measuring devices such as syringes and measuring cups to ensure the exact dose is prepared.

Many medications have standard dosing for adults based on the severity of the disease or comorbidity being treated. Other medications, such as Warfarin, are dosed based on therapeutic levels. These medication dosages can be adjusted because treatment can change based on the patient's status, the advancement or improvement of a condition, and how much the body can tolerate.

Some individuals in long-term care may have medical conditions that make it difficult to swallow pills by mouth. If this is the case, some medications may be crushed and mixed into food, such as applesauce. Always check your MAR, label, or with your pharmacist to confirm if a medication can be crushed or split because some medications are not meant to be split or crushed, such as extended-release medications. If you mix medications in food, always confirm that all the food has been consumed. If not all the food is consumed, medication may be left behind, resulting in only a partial dose being administered. Never leave a resident’s room until you know the medication has been taken.

Right Route

There are many routes for medication administration that nurses need to understand and feel confident with. Varying routes allow for different absorption rates. These varying absorption rates alter how quickly a medication is utilized within the body. Some medications are meant to be absorbed quickly, while others are made to have a delayed release or be processed over an extended time frame. Common routes for medication administration in long-term care include intravenous (IV), intramuscular (IM), inhalation, subcutaneous (SQ), oral (PO), sublingual, buccal, topical, intravaginal, intraocular, otic, intranasal, rectal, and transdermal. This course will discuss some of these methods and their indications and benefits. Certain medications are only indicated for certain routes because of their composition or mechanism of action, and administering medications through an improper route can cause bodily harm or life-threatening complications.

Right Time

Timing is critical to ensure that medications work to their maximum benefit. Administering a medication too often or too early can result in accidental medication overdose. If a medication is not given frequently enough or too late, complications can arise from the delayed administration. Medication orders include a specific time or times that the medication must be administered. Pay careful attention and administer medications as close to the prescribed time as possible. Important items to remember include the following.

  • Typically, in long-term care, routine orders have a window of one hour before and one hour after the prescribed time to administer the medication.
  • Time-sensitive medications must always be given as soon as possible. Many medications are given at specific intervals to ensure that the medications are processed and can be utilized before the previous dose wears off.  This is imperative with certain medications, such as cardiac, psychiatric, and blood-thinning medications.
  • Some medications are given on a PRN (as needed) basis, such as analgesics, sleeping medications, and anxiety medications.  Nurse discretion can be utilized to support and care for the resident.
  • In pain management, administering the medication when directed can help regulate pain control before the previous dose of the medication wears off and the pain becomes more intense. Always document when medications are given so that the next dose can be given at the correct time.

The right time also includes administering medications at the correct rate. This pertains to medications given via a pump or administered by hand, such as intravenous (IV) push medication.

  • Some medications must be administered over a set period of time to reduce side effects and harm. For example, IV pain analgesics, like morphine, are to be administered over 4-5 minutes to prevent side effects and to allow the body to absorb it (Medscape, 2025).
  • Nurses also need to be aware that some medications need to be administered slowly to prevent severe injury. Potassium, for instance, can cause severe tissue damage if infiltrated.
  • Some medications have an extremely short half-life, such as Adenosine. Adenosine has a half-life of approximately 10 seconds, which requires nurses to quickly push the medication and follow with a saline flush to allow the body to process the medication before it is depleted.
  • Some medications that are taken orally are an extended-release version, meaning that the tablet or capsule dissolves slowly so that the body absorbs the necessary amount over a period of time. These medications should not be crushed or altered.
  • While nurses are most often the ones giving medications to patients, there are some instances in which a patient has control over how much medication is received, such as with patient-controlled analgesics (PCA) pumps. In this scenario, nurses oversee medication administration and have orders to follow. However, the patient can push a button to deliver more medication as needed, while still having a limit

Paying careful attention to drug administration orders ensures that medications are given at the correct time and rate, which prevents medication errors and bodily harm, and maintains patient safety.

Expiration dates of medications are another aspect of time in proper medication administration. Always check for the expiration date to confirm that the medication you are administering has not expired. Expired medications are not safe and may not be as effective, which can have negative impacts on the individual who needs a specific amount of medication for treatment. Additionally, be aware of expiration dates on food used during medication administration, such as when crushed medications are added to applesauce.

Medication Routes

There are multiple routes for medication administration. Many medications can only be given through certain routes. Additionally, specific medications may be ordered for a specific route depending on an individual’s situation. Confidence in administering medications through all routes can prevent medication errors and protect the safety of the residents. Let’s discuss some of the common medication routes that are used in long-term care.

Route of Administration

graphic showing route of administration

Oral (PO)

Oral medications are extremely common and routine in long-term care facilities. Oral medications are taken through the mouth and absorbed into the bloodstream. The benefits of the oral route are that a wide variety of medications can be administered this way, and it is painless. Oral medications can be difficult for some residents with cognitive impairments who may not want to take the medication or may not understand why they are being asked to consume it. Oral medications may also be a problem for patients with dysphagia or digestive issues. Depending on the medication, oral medications can be tablets, capsules, or liquids. Many healthcare providers prescribe medications through this route because it requires little intervention or invasive means.

Medications administered through an enteral tube are also administered through the digestive tract, bypassing the mouth. Before administering medications through a feeding tube, always check for placement. Feeding tubes can become dislodged because of movement, coughing, and sneezing. Improper placement can lead to food being administered into the lungs, causing life-threatening aspiration pneumonia. Placement of a feeding tube can be confirmed by imaging, observing incremental markings on the tube itself, aspirating stomach contents, and checking the pH of stomach contents (Ernstmeyer & Christman, 2023). Maintain a patent tube by flushing it after medication administration so that no medication stays in the tube and is not delivered to the individual when not intended. Utilize oral syringes for oral medications so they are not confused with IV syringes.

Intravenous (IV)

One of the most common routes for medication administration is intravenous. This is commonly used in a hospital setting, but can also be used in a long-term care facility. Medications administered intravenously are given through a vein; thus, they are directly delivered to the circulatory system and carried throughout the body. Various medications can be given intravenously, including antibiotics, blood pressure medications, TPN and lipids, pain medications, potassium, fluids, etc. These IV entry points are often found in the hand or arm, but can also be accessed in the feet or jugular vein. Because of the direct access to the bloodstream, medication absorption occurs quickly. An IV can be used many times if properly cared for. The intravenous route is more invasive than the oral route. Disadvantages include the fact that some people do not tolerate the pain of placing the IV well, the IV must be maintained properly to prevent clotting and damage, and it increases the risk for infection due to the direct access to the bloodstream and the penetration of the skin.

Central venous catheters are used for patients who may require longer medication treatment and need a more stable venous access than a regular IV. These may also be indicated for specific medications or substances, such as TPN or lipids, or when long-term medication administration is required, as can be the case with some antibiotic treatments. Peripherally inserted central catheters (PICC) are one example of a central venous catheter. Due to the proximity to the heart and the direct access to the circulatory system, central lines are treated with extreme caution and care. Sterile and routine dressing changes are required to maintain a healthy site and prolong the central line's usage. Many other forms of central lines are used in healthcare settings and are not discussed in this course. It is important to know central lines, their indications, and how to care for them.

Intramuscular (IM)

Intramuscular (IM) refers to medications given into the muscle. IM injections are given in thick muscle tissue, such as the buttocks, thighs, or biceps. The IM route is often used for analgesics, epinephrine, naloxone, antibiotics, and vaccines. The medication is injected into the muscle through this route, where it is absorbed and transferred into the bloodstream. It is effective when venous access is not required or there isn’t time to obtain venous access (administering epinephrine during an anaphylactic reaction), when oral medications are not tolerated, or in a situation where a patient needs a medication but is not compliant (such as with an agitated and confused patient needing haloperidol)(Kim & De Jesus O, 2023). There are varying gauges of needles used in IM injections based on the size of the patient and the muscle, as well as the thickness of the substance being injected. This route is commonly used in outpatient settings and has relatively low risks.

Subcutaneous (SQ)

SQ stands for the subcutaneous route. Subcutaneous refers to the fatty tissue found between the skin and the muscle. This injection form is less common, but is used in specific medication administration, such as insulin, monoclonal antibodies, and blood thinners like heparin. The most common places for a subcutaneous injection are in the fatty tissue of the stomach, the front of the thigh, or the underarm. If administering the medication in the stomach, avoid the 2 inches around the navel (Kim & De Jesus O, 2023). Such injections are given by pinching the skin to gather the subcutaneous tissue and inserting a small needle to deliver the medication. The subcutaneous route is used when a medication needs a faster absorption/bioavailability than the oral route can provide, or when the intestinal tract can’t effectively absorb the drug due to its molecular size (Kim & De Jesus O, 2023).

Types of Injections

graphic showing types of injections

Inhalation (INH)

Inhalation is an effective route for medication administration because the lungs have a large surface area, which allows for increased absorption. Additionally, the lungs are in close proximity to blood flow (Kim & De Jesus O, 2023). Inhaled medications are most commonly used for respiratory conditions or infections, such as asthma, COPD, or bronchitis. Steroids for respiratory conditions are commonly administered through inhalation. Administering medications through this route requires careful monitoring and proper training so that the individual receives the right amount of medication within a specific time frame. Specialized equipment to dispense the medication is required for administering these medications (Le, 2024). This may include an inhaler device or a nebulizer. Inhaling medication allows for direct dispersion to the lungs and, thus, is extremely effective for individuals who require this type of medical treatment.

Sublingual or Buccal

Sublingual means “under the tongue”, and buccal means “cheek.” Medications taken by these routes dissolve and do not require chewing or swallowing. Medications administered through these routes are absorbed more quickly than when taking medications orally (PO) because they are absorbed through the tissue under the tongue or between the gum and the cheek, and are transferred into the bloodstream. Medications absorbed via the sublingual or buccal route bypass the liver, which is beneficial in some instances. For example, Nitroglycerin is administered sublingually. If it were to be taken by mouth, the liver would clear approximately 90% of the medication, which decreases its effectiveness significantly (Kim & De Jesus O, 2023). This route is quick, painless, convenient, and has a low risk of infection.

Other Routes

There are many other routes for medication administration, many of which target the area, organ, or tissue directly affected. Examples that are common in a long-term care setting include:

  • Intravaginal: Hormonal medications are commonly administered intravaginally. These medications may be a cream, gel, ring, suppository, solution, or tablet. During menopause, estrogen is often given vaginally to relieve uncomfortable symptoms associated with menopause (Le, 2024).
  • Rectal: This route allows for quick absorption, can be used in emergencies, has low risk factors, and can administer large amounts of medication. It is also often used for patients with digestive tract complications that may interfere with the absorption of oral medications (Kim & De Jesus O, 2023). The disadvantage is that it can be embarrassing or uncomfortable for some patients.
  • Intraocular: Medications used to treat local eye conditions, such as dry eyes, glaucoma, conjunctivitis, or even injuries, are often administered through the eye (Le, 2024). Medication delivery through this route is effective but can be stressful for the patient. For intraocular medication, it is important to use gloves and not touch the eye with the dropper.
  • Topical: These medications are administered on the skin and can target the specific part of the skin affected by a condition, infection, or disease. They are in the form of gels, lotions, ointments, powders, solutions, or creams. Examples include antifungals, antibacterials, or steroids (Le, 2024).
  • Transdermal: Medication is delivered through the skin and enters the bloodstream. This can include gels, ointments, and transdermal patches, such as fentanyl patches (Kim & De Jesus O, 2023)
  • Otic: Medication is delivered through the ear, typically through the outer ear canal. This route treats ear issues, such as infection or inflammation. Examples of medications that are administered in the ear are hydrocortisone (to relieve inflammation), ciprofloxacin (to treat infection), and benzocaine (to numb the ear) (Le, 2024).
  • Intranasal: Medication is delivered through the nose. Medications given through this route are typically decongestants for allergies or colds. Recently, the FDA approved an epinephrine nasal spray for the treatment of anaphylaxis (US Food & Drug Administration, 2024). Other medications that can be given through this route are used for treating diabetes insipidus or osteoporosis. These medications are absorbed in approximately 30 minutes and are easy to administer. The nasal mucosa also has increased permeability compared to the gastrointestinal mucosa (Kim & De Jesus O, 2023).

Proper Medication Preparation

Proper medication preparation is a key aspect of successful and safe medication administration. Incorporating key practices in medication preparation can foster an environment of success, accuracy, and safety. Proper medication preparation includes infection prevention, eliminating distractions and interruptions, allergy accountability, and pre-administration assessments.

Infection Prevention

Medication preparation can be a potential source for spreading bacteria and viruses if it is not done with caution.

  • Maintain a clean medication cart or station free from clutter and mess.
  • Always disinfect the area.
  • Always wash your hands and use gloves to prepare medications. Washing hands with soap and water is the most effective way of cleaning your hands. Hand sanitizer is appropriate in many instances, but hand washing should always be done when hands are visibly soiled.
  • Always use hand hygiene when entering and exiting patient rooms to prevent the spread of disease.
  • Place medications directly in a medication cup or syringe.
  • If you use a syringe, always cap it.
  • If using a pill cutter or crusher, ensure it has been cleaned.
  • If you drop a pill, throw it away.

Eliminate Distractions and Interruptions

Creating a distraction- and interruption-free preparation space can improve medication administration and reduce the chances of errors during preparation.

  • Keep the medication cart or station organized without any personal items.
  • Limit distractions by informing others in your facility that you are preparing medications.
  • Medications must also be prepared for one individual at a time. Preparing multiple medications for multiple individuals can lead to confusion and accidental medication errors.

Allergy Accountability

Reviewing resident allergies is one of the duties of a nurse and an essential step in medication preparation. Allergies to medications, foods, and the environment should be documented in a resident’s chart in an obvious location. Reviewing allergies can help prevent dangerous medication errors. Residents should never be prescribed a medication they are allergic to. However, reviewing allergies before medication administration is a way to catch errors and maintain the safety of those within the facility.

Assess Before You Pass

An important aspect of medication administration is understanding why a medication is being given, how the medication works, and assessing the patient before medication administration. Pre-administration vitals should be assessed for some medications, such as blood pressure and pain medications. For instance, if a patient is experiencing a fever and PRN acetaminophen is appropriate, assess the individual’s temperature before administration and after the acetaminophen has had a chance to take effect. Assess pain scores before administering an analgesic, and again post administration. Many other medications require pre-administration assessments. Nurses must use critical thinking skills to recognize what assessments must be completed. Nurses are trained to recognize abnormalities, and it is their duty to respond appropriately in terms of medication administration, which, at times, may include withholding a medication if it is deemed unsafe to administer. In such a situation, notify the prescribing provider immediately and document. Assess the resident and the situation; don’t just pass the medication.

Case Study #1

Sarah is a nurse working in a long-term care facility. She arrives at work and begins to prepare medications for the residents. Mr. Smith, an 80-year-old resident, is due for his 0700 dose of Metoprolol for hypertension. Upon reviewing his morning vital signs, the CNA documented a blood pressure reading of 90/60. Sarah recognized that this blood pressure reading was lower than usual and took a manual one. The manual reading was the same, and the resident complained of slight dizziness. Using her premedication assessment knowledge, Sarah withholds the morning dose of Metoprolol and immediately notifies the prescribing provider. The provider agrees that Mr. Smith should not receive the morning dose of Metropol and needs further evaluation. Sarah documents withholding the medication, her notification to the provider, and the provider's orders. Sarah continues to monitor Mr. Smith. Nurse Sarah used her assessment skills, medication knowledge, and critical thinking to assess Mr. Smith’s condition before administering his morning medications. She also appropriately double checked the blood pressure that the CNA collected. She avoided administering a medication that could have further lowered Mr. Smith’s blood pressure and caused serious complications.

Documentation of Medication Administration

Thorough, accurate, complete, and timely documentation is critical in healthcare. Proper documentation helps record what medications have been administered, what procedures have been completed, and the resident/patient’s status.

  • Always document what medication is given, to whom, when, how, and the dosage. Always document administration immediately after it has been given, not before. Sometimes, a patient may refuse a medication or spit it out. In this circumstance, having documented that a medication was already given causes issues.
  • In long-term care, medications typically have a 1-hour window before and after the prescribed time to administer the medication. Consider this when planning medication administration to ensure all patients receive their medications as needed. Certain medications, such as pain medications, may need to be given early in the allowed window to prevent pain.
  • When assessments are required before administration, such as blood pressure or pain score, ensure that these are documented as well. Proper documentation helps you, as the nurse caring for residents and oncoming nurses, understand what was given, when, and why.
  • Any education regarding medications that is provided to residents should be documented accordingly.
  • Always document a resident's refusal of medication.

Thorough, detailed, and accurate documentation in nursing care, including medication administration, what patient care has occurred, how it was performed, and when, is critical. If it wasn’t documented, there is no record that it was done. Documentation protects patients as well as nurses.

Medication Caution

An important aspect of medication administration is recognizing that some medications have higher risks associated with them. This pertains to all areas of healthcare, including long-term care. Specific medications have a higher risk for those who are older or have specific medical conditions. Learning how to recognize these medications is an important skill for nurses, and knowledge of these medications can decrease the incidence of harm from medications or medication errors.

High-Alert Medications

The Institute for Safe Medication Practices (ISMP) defines high-alert medications as “drugs that bear a heightened risk of causing significant patient or resident harm when they are used in error (wrong drug, wrong dose, wrong route, wrong resident)(2021).” Nurses should be aware of such medications to promote resident safety.

Classes/Categories of High-Alert Medications in Long-Term (LTC) Settings (ISMP, 2021)
  • Anti-Parkinson’s drugs
  • Antithrombotic agents
  • Chemotherapeutic agents
  • GABA analogs
  • Immunosuppressants
  • Insulins (includes all formulations and strengths)
  • Opioids (includes all routes of administration)
  • Parenteral nutrition preparations
  • Sulfonylurea hypoglycemics (oral)
Specific High-Alert Medications (ISMP, 2021)
  • Concentrated morphine solution (20 mg/mL), oral
  • Digoxin, parenteral and oral
  • Epinephrine, IM, subcutaneous
  • Insulin U-500
  • Iron dextran, parenteral
  • Methotrexate, oral and parenteral, nononcologic use
  • Phenytoin
  • Sacubitril and valsartan (Entresto)

The Beers Criteria

Another tool to aid in safe medication administration is the Beers Criteria. The American Geriatrics Society created “The Beers Criteria for Potentially Inappropriate Medication Use in Older Adults” to help providers safely prescribe medications to people 65+ (Cleveland Clinic, 2023). These criteria can be helpful for nurses to reference when caring for residents in long-term care.

The Beers Criteria includes (Cleveland Clinic, 2023):

  • Medications to avoid if you’re over 65 years old and not in a hospice or palliative care setting
  • Medications to avoid among those with certain health conditions
  • Medications to avoid that can cause drug-drug interactions
  • Medications to avoid because of harmful side effects that outweigh the benefits
  • Medications that should be used at limited doses or avoided because of their impact on kidney function

“The Beers List” contains almost 100 medications. The Cleveland Clinic has provided a list of some of the medications that are on that list and why they are dangerous (Cleveland Clinic, 2023):

The Beers List (Partial List) (Cleveland Clinic, 2023)
MedicationWhy is it dangerous?
Analgesics (Meperidine)Neurotoxicity, delirium
Antibiotics (ciprofloxacin with warfarin)Increased bleeding
Antiseizure medications (carbamazepine)Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Antihistamines (brompheniramine)Confusion, cognitive impairment, delirium
Antihypertensives (alpha-blockers)Hypotension
Antiplatelets or anticoagulants (edoxaban)Renal impairment
Antipsychotics (any)Stroke, cognitive decline, delirium
Anxiolytics (benzodiazepines)Impaired metabolism, cognitive impairment, unsteady gait
Cardiac medications (disopyramide)Heart failure
Central nervous system agents (dimenhydrinate)Confusion, cognitive impairment, delirium
Diabetes medications (chlorpropamide)Hypoglycemia
Gastrointestinal medications (H2-blocker for delirium)Worsening delirium
Hormones (estrogen)Breast cancer, endometrial cancer
Hypnotics (barbiturates)Dependence, overdose
Musculoskeletal agents (muscle relaxers)Confusion, dry mouth, constipation
NSAIDs [aspirin (over 325 mg/day)]Ulcer, gastrointestinal bleeding, or perforation
Respiratory medications (atropine)Confusion, cognitive impairment, delirium
Urinary medications (desmopressin)Low sodium in blood (hyponatremia)
Vasodilators (ergoloid mesylates)Lack of intended results

Click here for the most updated American Geriatric Society Beers Criteria(AGS, 2023).

Recognizing which medications have higher risks and why they can harm individuals is essential to medication administration. Knowing how high alert medications work, why and when they are prescribed, and what precautions must be taken will improve patient safety and prevent inappropriate medication administration. Having reference lists on medication carts can be a resource for nurses preparing medications. Thorough training on high-alert medications must be prioritized. This will improve patient care.

Drug Interactions

While administering medications, it is crucial to recognize the reality of drug interactions and the negative impacts they can have. Residents in long-term care often have multiple chronic conditions or may be in long-term care because of significant medical conditions like Alzheimer’s Disease. Due to underlying conditions, many individuals take multiple medications and may be at higher risk of drug interactions.

The types of drug interactions are (Cleveland Clinic, 2025):

  • Drug-drug interactions
  • Drug-food/beverage interactions
  • Drug-supplement interactions
  • Drug-condition interactions

Recognizing how drug interactions can affect those you administer medications to is important in understanding just how dangerous some drug interactions can be.

Drug interactions can cause (Cleveland Clinic, 2025):

  • Side effects or toxicity that are uncomfortable and/or dangerous
  • Increased effectiveness of the medication, causing it to do more than it is supposed to
  • Decreased effectiveness, in which a medication does not work as it is intended because of what it is interacting with

Some medications may need to be avoided based on medical history or current conditions, like kidney or liver disease. Drug interactions can also occur with over-the-counter medications. Make sure any medications you are giving a resident are ordered by a provider, including over-the-counter medications. Supplements can have interaction risks. For instance, St. John’s wort is an herbal supplement that has many dangerous drug interactions, and nurses need to be aware of it. It can lead to serotonin syndrome if taken with SSRIs (selective serotonin reuptake inhibitors). Other common supplements that may interact include garlic extracts, goldenseal, and concentrated green tea supplements (Cleveland Clinic, 2025).

Understanding drug interactions is important to pharmacology and can improve patient safety and well-being. In long-term care, some residents find themselves in a unique situation where they require medical care or assistance, yet are still independent in other ways. Help residents understand drug interactions with medications they take so they can also take part in avoiding certain supplements, medications, or foods that may impact the medications they are currently taking. You may also need to remind them of certain foods or drinks to avoid. Nurses can use many books, apps, and websites to check for interactions. Always use credible and up-to-date sources. Pharmacists are also an excellent reference for medication questions. Utilizing the available tools and resources can make your nursing role less overwhelming and help you provide exceptional care.

Preventing Medication Errors

According to the National Coordinating Council for Medication Error Reporting and Prevention (NCCMERP), a medication error is defined as “any preventable occasion that may cause, or prompt improper medicine use or patient harm while the medicine is in the control of the healthcare worker, patient, or buyer” (Alrabadi et al., 2021). Striving to prevent medication errors is critical for patient safety and overall well-being. Medication errors can be broken down into four main classifications (Alrabadi et al., 2021).

  • Knowledge-based errors learning absence):  A gap in knowledge leads to a medication error, such as not knowing a patient’s allergies or the warnings about a specific medication.
  • Rule-based errors (utilizing a terrible standard or twisting a decent principle):  This includes failing to follow the rules or guidelines of a medication, such as administering a medication through the wrong route.
  • Activity-based errors (slips):  These errors occur when the appropriate knowledge is present, but an error occurs when completing the task. For example, a nurse accidentally administers Buspirone instead of Bupropion because the medications' names look alike. In this instance, tall man lettering can play a part in reducing medication errors, which will be discussed later in the course. 
  • Memory-based errors (memory lapse):  forgetting medication knowledge or patient information that causes an error. For example, a nurse forgets that a patient is allergic to a medication and administers it.

Extra precautions and circumstances can be taken to further decrease the incidence of medication errors and best support an environment in which they are less likely to occur. Following the five rights of medication administration can help significantly reduce the chances of a medication error.

A survey of nurses found that some of the main causes of medication errors could be traced back to (Alrabadi et al., 2021):

  • Illegible handwriting
  • Interruptions and distractions
  • Lack of pharmacological knowledge
  • Calculation errors
  • Not considering lab tests
  • Working overtime
  • Absence of self-awareness
  • Organizational factors such as training
  • Failure to follow protocols
  • Mental and physical health considerations

Nurses must be aware of common medication errors and how to prevent them. Some important strategies to prevent medication errors are as follows:

  • Two nurses are required when wasting narcotics to avoid administering the wrong dose, as well as to prevent controlled substances from being stolen.
  • Nurses should verify any known allergies and acknowledge allergy indicators on wristbands and resident charts.
  • Adherence to the five rights of medication administration.
  • With such a vast array of medications, generic and brand names, and different compositions, it is important to familiarize oneself with a medication before giving it. Nurses should never administer medications without knowing what they are administering and what it is for.
  • Unfortunately, sometimes, a provider may prescribe a medication or dosage that a nurse may be uncomfortable giving to a resident because the nurse feels it is inappropriate or unsafe. If this is the case, nurses should refuse to administer the medication to protect the patient and themselves. If a nurse is uncomfortable, this should be vocalized, and the appropriate person should be notified.
  • Effective communication reduces the likelihood of harmful medication errors. When taking a verbal order from a prescribing healthcare provider, it is best practice to repeat back the medication order and receive confirmation that it is correct. This prevents misinterpretation and helps to confirm what is being administered.
  • Medication administration is within the scope of practice for nurses. It should never be delegated to another healthcare professional or individual who is not licensed to do so. Never have someone give a medication for you, and never administer a medication you have not prepared yourself. You do not want to give a medication incorrectly, and you do not want to be responsible for someone else’s medication error.
  • Do not administer medications by memory. This is very dangerous because prescriptions can change, and memory lapses can occur.
  • Prepare one patient’s medications at a time. This decreases the chance of a medication error, where the medication is given to the wrong individual.
  • Utilizing computer systems for medication administration is extremely beneficial. Electronic prescribing and computer verification methods can catch human error and prevent medication errors.
  • Residents often become familiar with their medications, their appearance, how often they take them, and how. If a resident questions a medication, stop immediately and verify that you have the correct medication.

Nurses must make every effort to avoid errors in medication administration. They must strive to foster a safe environment for the residents and all those who care for them. Thoroughness and attention to detail when preparing and administering medications can prevent dangerous medication errors.

Nurses have a professional and ethical obligation to accurately and promptly document a medication error in the patient's record and report it to their facility's incident reporting system, which is crucial for patient safety and improving medication practices. This obligation stems from legal responsibilities, professional standards, and the ethical duty to maintain accurate records, ensure patient safety, and contribute to a culture of safety and continuous quality improvement (Catamco, 2025).

Dangers of Medication Abbreviations

Using abbreviations when prescribing or documenting medications is extremely dangerous. Abbreviations leave room for misinterpretation and confusion. To prevent abbreviation errors, the official “Do Not Use” list was created. Nurses should follow this list to prevent medication errors.

The most recent list of abbreviations to avoid, as per The Joint Commission (TJC):

Official "Do Not Use" List (TJC, n.d.)
Do Not UsePotential ProblemUse Instead
U, u (unit)Mistaken for "0" (zero), the number "4" (four), or "cc"Write "unit"
I.U. (International Unit)Mistaken for IV (intravenous) or the number 10 (ten)Write "International Unit"
Q.D., Q.D., q.d., qd (daily)

Q.O.D., Q.O.D., q.o.d, qod(every other day)
Mistaken for each other

Period after the Q mistaken for "I" and the "O" mistaken for "I"
Write "daily"

Write "every other day."
Trailing zero (X.0 mg)*

Lack of leading zero (.X mg)
The decimal point is often missedWrite X mg

Write 0.X mg
MS

MSO4 and MgSO4
It can mean morphine sulfate or magnesium sulfate

Confused with one another
Write "morphine sulfate"

Write "magnesium sulfate"

The rules regarding not using these abbreviations apply to all orders and medication-related documentation that is handwritten (including free-text computer entry) or on pre-printed forms.

*Exception: A "trailing zero" may be used only where required to demonstrate the level of precision of the value being reported, such as for laboratory results, imaging studies that report the size of lesions, or catheter/tube sizes. It may not be used in medication orders or other medication-related documentation.

Tall Man Lettering Technique

More medication errors can occur when medications have similar names. To aid in preventing medication errors related to medication names, the technique of Tall Man Lettering (TML) was implemented. This technique includes capitalizing dissimilar letters in drug names to draw attention to these differences and prevent the inappropriate medication from being administered.  When determining when to use TML, the Federal Drug Administration (FDA) analyzes the following factors (Federal Drug Administration [FDA], 2020)

  • Degree of similarity between the name pair
  • Safety risks associated with the medications
  • Overlapping product characteristics
  • Reports of errors about the drug
  • Causes or contributing factors 

After determining the need for TML, the FDA will contact the manufacturer and ask that they incorporate TML into their labels for the specific medication(s) (FDA, 2020). The FDA provides a list of drug names that they recommend utilize TML. Nurses should familiarize themselves with this list to become more aware of these medications.

FDA List of Established Drug Names Recommended to Use Tall Man Lettering (TML) (FDA, 2020)
Established NameRecommended Name
Acetohexamide
Acetazolamide
acetoHEXAMIDE
acetaZOLAMIDE
Bupropion
Buspirone
buPROPion
busPIRone
Chlorpromazine
Chlorpropamide
chlorproMAZINE
chlorproPAMIDE
Cisplatin
Carboplatin
CISplatin
CARBOplatin
Clomiphene
Clomipramine
clomiPHENE
clomiPRAMINE
Cyclosporine
Cycloserine
cycloSPORINE
cycloSERINE
Daunorubicin
Doxorubicin
DAUNOrubicin
DOXOrubicin
Dimenhydrinate
Diphenhydramine
dimenhyDRINATE
diphenhydrAMINE
Dobutamine
Dopamine
DOBUTamine
DOPamine
Glipizide
Glyburide
glipiZIDE
glyBURIDE
Hydralazine
Hydroxyzine
hydrALAZINE
hydrOXYzine
HydromorphoneHYDROmorphone
Medroxyprogesterone
Methylprednisolone
Methyltestosterone
medroxyPROGESTERone
methylPREDNISolone
methylTESTOSTERone
Methylprednisolone
Methyltestosterone
methylPREDNISolone
methylTESTOSTERone
Migalastat
Miglustat
migALAstat
migLUstat
MitoxantronemitoXANTRONE
Nicardipine
Nifedipine
niCARdipine
NIFEdipine
Prednisone
Prednisolone
predniSONE
prednisoLONE
Risperidone
Ropinirole
risperiDONE
rOPINIRole
Sulfadiazine
Sulfisoxazole
sulfADIAZINE
sulfiSOXAZOLE
Tolazamide
Tolbutamide
TOLAZamide
TOLBUTamide
Trazodone
Tramadol
traZODone
traMADol
Vinblastine
Vincristine
vinBLAStine
vinCRIStine

Case Study #2

Dave is a nurse who works in a long-term care facility. He arrives at work and begins to prepare medications due at 1900. He has multiple residents needing medications. He understands the importance of preparing medications for one individual at a time. He begins to prepare medications for Ann Jones. He verifies the five rights of medication administration before and after preparing the medications and compares the medications to the MAR. Upon entering Mrs. Jones’ room, Dave asks her to confirm her name and date of birth. Upon hearing her response, he realizes her date of birth does not match the MAR. Dave realizes that two residents named Ann Jones are in the long-term care facility and that the medications he has prepared are for a different resident. Upon recognizing this error, he was able to then prepare the correct medications for Mrs. Jones. Dave successfully utilized the five rights of medication administration and used two resident identifiers, preventing a medication error. Had he not thoroughly verified using two patient identifiers, Mrs. Jones would have received the incorrect medications, and this could have potentially caused severe bodily harm.

Conclusion

Medication administration is a routine part of healthcare, with millions of individuals benefiting from a wide variety of medications for various conditions. While very beneficial, the risk of medication errors is still a problem that the healthcare world faces. Continuing to educate oneself and create a safer patient environment leads to reduced medication errors and resident harm. Administering the correct medication to the right patient, with the correct dose and route, at the right time, are steps to foster safe medication administration. Awareness of common errors and how to prevent them is the first step in preventing dangerous medication errors in long-term care.

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Implicit Bias Statement

CEUFast, Inc. is committed to furthering diversity, equity, and inclusion (DEI). While reflecting on this course content, CEUFast, Inc. would like you to consider your individual perspective and question your own biases. Remember, implicit bias is a form of bias that impacts our practice as healthcare professionals. Implicit bias occurs when we have automatic prejudices, judgments, and/or a general attitude towards a person or a group of people based on associated stereotypes we have formed over time. These automatic thoughts occur without our conscious knowledge and without our intentional desire to discriminate. The concern with implicit bias is that this can impact our actions and decisions with our workplace leadership, colleagues, and even our patients. While it is our universal goal to treat everyone equally, our implicit biases can influence our interactions, assessments, communication, prioritization, and decision-making concerning patients, which can ultimately adversely impact health outcomes. It is important to keep this in mind in order to intentionally work to self-identify our own risk areas where our implicit biases might influence our behaviors. Together, we can cease perpetuating stereotypes and remind each other to remain mindful to help avoid reacting according to biases that are contrary to our conscious beliefs and values.

References

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